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Neuropeptide FF CAS NO.99566-27-5
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Keywords
- NPFF
- H-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2
Quick Details
- ProName: Neuropeptide FF
- CasNo: 99566-27-5
- Molecular Formula: C54H76N14O10
- Appearance: White lyophilised solid
- Application: Narcotic Antagonists
- Purity: ≥95% by HPLC
- Storage: Store at -20°C
- LimitNum: 0
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Details
Neuropeptide FF, which belongs to the RF-amide family of peptides, is an endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki= 2.82 and 0.21 nM respectively). Neuropeptide FF has anti-opioid effects in rodent models, inhibiting morphine-induced analgesia and inducing abstinence in morphine-tolerant rats. It also inhibits acquisition of conditioned place preference to cocaine in rats when administered at doses of 10 and 20 nmol.
