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Riviciclib HCl CAS NO.920113-03-7
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Keywords
- 2-(2-chlorophenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl)-4H-chromen-4-one hydrochloride
- P276-00
Quick Details
- ProName: Riviciclib HCl
- CasNo: 920113-03-7
- Molecular Formula: C21H21Cl2NO5
- Appearance: Solid powder
- Application: For research use only.
- Purity: 95%
- Storage: Store in a cool and dry place (or refe...
- LimitNum: 0
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Details
Riviciclib, also known as P276-00, is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. P276-00 selectively binds to and inhibits Cdk4/cyclin D1, Cdk1/cyclin B and Cdk9/cyclin T1, serine/threonine kinases that play key roles in the regulation of the cell cycle and cellular proliferation.
