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Bosutinib monohydrate CAS NO.918639-08-4
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- Product Details
Keywords
- Bosutinib hydrate
- 3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-, hydrate (1:1)
Quick Details
- ProName: Bosutinib monohydrate
- CasNo: 918639-08-4
- Molecular Formula: C26H29Cl2N5O3.H2O
- Appearance: Pale Yellow Solid
- Application: For research use only.
- Purity: ≥95%
- Storage: Store at 2-8 °C
- LimitNum: 0
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Details
Bosutinib hydrate is a Src/Abl inhibitor used in the treatment of chronic myeloid leukemia (CML), a type of cancer that affects the blood and bone marrow. Bosutinib is a tyrosine kinase inhibitor that works by blocking the activity of BCR-ABL, a protein that promotes the growth of abnormal leukemia cells in patients with CML. BCR-ABL is formed as a result of a genetic abnormality known as the Philadelphia chromosome. It is indicated for the treatment of adults with newly diagnosed chronic phase CML as well as CML that is resistant or intolerant to prior therapy, including imatinib.
