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(Z)-4EGI-1 CAS NO.901787-88-0
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Keywords
- (2Z)-2-{[4-(3,4-Dichlorophenyl)-1,3-thiazol-2-yl]hydrazono}-3-(2-nitrophenyl)propanoic acid
- Benzenepropanoic acid, α-[2-[4-(3,4-dichlorophenyl)-2-thiazolyl]hydrazinylidene]-2-nitro-, (αZ)-
Quick Details
- ProName: (Z)-4EGI-1
- CasNo: 901787-88-0
- Molecular Formula: C18H12Cl2N4O4S
- Application: For research use only.
- Purity: ≥98%
- Storage: Store at -20°C
- LimitNum: 0
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Details
(Z)-4EGI-1, the Z-isomer of 4EGI-1, is an inhibitor of eIF4E/eIF4G interaction and translation initiation and has anticancer activity. It effectively binds to eIF4E with an IC50 of 43.5 μM and a Kd of 8.74 μM.
