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Arachidonoyl amide CAS NO.85146-53-8
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Keywords
- Arachidonamide
- Arachidonic acid amide
Quick Details
- ProName: Arachidonoyl amide
- CasNo: 85146-53-8
- Molecular Formula: C20H33NO
- Appearance: Colorless Oil
- Application: For research use only.
- Purity: ≥98%
- LimitNum: 0
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Details
Arachidonamide (AEA) is a weak cannabinoid CB1 and CB2 agonist. Arachidonamide was hydrolyzed by FAAH more effectively than AEA but exhibited significantly weaker binding to the human CB1 receptor with a Ki of 9.6 μM. AEA also inhibits rat glial gap junction cell-cell communication by 90% at a concentration of 20 μM. Arachidonamide are found to be the best substrates for anandamide amidohydrolase (AAH) with relative rates of hydrolysis about twice that of anandamide.
