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BX-517 CAS NO.850717-64-5
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Keywords
- (Z)-N-(3-(1-(1H-pyrrol-2-yl)ethylidene)-2-hydroxy-3H-indol-5-yl)carbamimidic acid
- BX-517
Quick Details
- ProName: BX-517
- CasNo: 850717-64-5
- Molecular Formula: C15H14N4O2
- Appearance: Solid powder
- Application: For research use only.
- Purity: 95%
- Storage: Store in a cool and dry place (or refe...
- LimitNum: 0
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Details
BX-517, also known as PDK1 inhibitor2, is a cell-permeable indolinone compound that acts as a potent, ATP site-targeting PDK1 inhibitor (IC50 = 6 nM). BX-517 also blocks activation of Akt in tumor cells with 10-fold more potent (IC50 = 0.1-1.0 μM) than its analogs tested at the highest dose tested (10 μM).
