- Product Details
Keywords
- cas 794466-17-4
- DAP 81
- 794466-17-4
Quick Details
- ProName: DAP-81
- CasNo: 794466-17-4
- Molecular Formula: C25H20N6O4
- Appearance: White Solid
- Application: Inhibitor
- DeliveryTime: 7 days
- ProductionCapacity: 1 Kilogram/Month
- Purity: 98%
- LimitNum: 1 Gram
Superiority
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
Details
DAP-81 is a diaminopyrimidine derivative that targets PLKs, destabilizing kinetochore microtubules. Other spindle tubules are stabilized, resulting in monopolar mitotic spindles. In vitro, DAP-81 inhibits Plk1 at an IC50 of 0.9 nM. DAP-81 is currently in ongoing preclinical evaluations.