Quick Details
- ProName: CAY10397
- CasNo: 78028-01-0
- Molecular Formula: C17H16N2O5
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥98%
- LimitNum: 0
Superiority
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Details
Prostaglandins are rapidly inactivated in vivo by the action of 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH). CAY10397 is a selective inhibitor of 15-hydroxy PGDH, significantly suppressing endogenous 11-oxo-ETE production with a corresponding increase in 11(R)-HETE. It is a selective inhibitor of 15-hydroxy PGDH with IC50 of 10 μM.