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Home > Products >  (-)-Neplanocin A

(-)-Neplanocin A CAS NO.72877-50-0

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Keywords

  • NPC-A
  • (-)-9-(trans-2,trans-3-Dihydroxy-4-(hydroxymethyl)-cyclopent-4-enyl)-adenine

Quick Details

  • ProName: (-)-Neplanocin A
  • CasNo: 72877-50-0
  • Molecular Formula: C11H13N5O3
  • Appearance: Colorless Acicular Crystal
  • Application: Antibiotics, Antineoplastic
  • Purity: ≥98%
  • Storage: Store at -20°C
  • LimitNum: 0

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Details

(?)-Neplanocin A potently and irreversibly inactivates SAH hydrolase (Ki = 8.39 nM). It has antitumor activity against mouse leukemia L1210 cells and broad-spectrum antiviral activity. Neplanocin A is more potent against vesicular stomatitis than the reversible SAH hydrolase inhibitor 3-deazaneplanocin (ID50 = 0.07 and 0.3 μg/ml, respectively).

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