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Syk Inhibitor II CAS NO.726695-51-8
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Keywords
- Spleen Tyrosine Kinase Inhibitor II
- 2-((2-Aminoethyl)amino)-4-((3-(trifluoromethyl)phenyl)amino)pyrimidine-5-carboxamide
Quick Details
- ProName: Syk Inhibitor II
- CasNo: 726695-51-8
- Molecular Formula: C14H15F3N6O
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥98%
- LimitNum: 0
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Details
Syk inhibitor II is a cell-permeable, ATP-competitive inhibitor of Syk (IC50 = 41 nM). It also exhibits less potent inhibitory effects against PKCε, PKCβII, ZAP-70, Btk, and Itk (IC50s = 5.1, 11, 11.2, 15.5, and 22.6 μM, respectively).
