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bpV(HOpic) potassium salt CAS NO.722494-26-0
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Keywords
- Bisperoxovanadium(HOpic)
Quick Details
- ProName: bpV(HOpic) potassium salt
- CasNo: 722494-26-0
- Molecular Formula: C6H4NO8V·2K
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥95%
- LimitNum: 0
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Details
BpV(HOpic) is a protein tyrosine phosphatases (PTPs) and a potent PTEN inhibitor with IC50 of 14 nM. It also inhibits the vascular endothelial PTP-β with IC50 of 4.9 μM and PTP-1βB with IC50 of 25.3 μM. It is reported to function as an insulin mimetic and activate the insulin receptor kinase (IRK). BpV(HOpic) has been shown to activate the insulin receptor kinase of hepatoma cells and enhance PI3K/Akt signaling, which could prevent ischemia-reperfusion (I/R) injury to the myocardium.
