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12(S)-HpETE CAS NO.71774-10-2
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Keywords
- 12-Hydroperoxyicosatetraenoate
- (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid
Quick Details
- ProName: 12(S)-HpETE
- CasNo: 71774-10-2
- Molecular Formula: C20H32O4
- Application: For research use only.
- Purity: ≥98%
- LimitNum: 0
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Details
12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons6 and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex.
