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BayCysLT2 CAS NO.712313-33-2
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Keywords
- CAY10633
- 3-[[(3-carboxycyclohexyl)amino]carbonyl]-4-[3-[4-(4-phenoxybutoxy)phenyl]propoxy]-benzoic acid
Quick Details
- ProName: BayCysLT2
- CasNo: 712313-33-2
- Molecular Formula: C34H39NO8
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥95%
- LimitNum: 0
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Details
BayCysLT2 is a potent and selective antagonist for the CysLT2R, which attenuates exacerbation of infarction damage to the myocardium caused by endothelial CysLT2R overexpression. CysLT2R can influence myocardial damage post-ischemia/reperfusion by mediating leukocyte adhesion and infiltration. CysLT2R can further blockade post-infarction maintains its protective properties, indicating a possible therapeutic role for CysLT2R antagonism. BayCysLT2 inhibits radioligand binding of LTD4 to CysLT2 and CysLT1 receptor cell lines with IC50 values of 35 and >10,000 nM, respectively.
