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RO8191 CAS NO.691868-88-9
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Keywords
- Ro 494-8191
- 2-[2,4-bis(trifluoromethyl)imidazo[1,2-a]1,8-naphthyridin-8-yl]-1,3,4-oxadiazole
Quick Details
- ProName: RO8191
- CasNo: 691868-88-9
- Molecular Formula: C14H5F6N5O
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥98%
- Storage: -20°C, stored under nitrogen
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Details
RO8191 is an agonist of interferon α receptor type 2 (IFNAR2) effective against HCV with EC50 value of 200 nM. RO8191 phosphorylates STAT1 and STAT2, which functions as a gateway to the type I IFN signal cascade, and stimulates the phosphorylation of STAT3, 5 and 6.
