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Glabrescione B CAS NO.65893-94-9
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Keywords
- 5,7-Dimethoxy-3',4'-diprenyloxyisoflavone
- 4H-1-Benzopyran-4-one, 3-[3,4-bis[(3-methyl-2-buten-1-yl)oxy]phenyl]-5,7-dimethoxy-
Quick Details
- ProName: Glabrescione B
- CasNo: 65893-94-9
- Molecular Formula: C27H30O6
- Application: For research use only.
- Purity: ≥98%
- Storage: Store at -20°C
- LimitNum: 0
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Details
Glabrescione B is the first compound to bind the Hedgehog (Hh) modulator Gli1 and impair its activity by interfering with Gli1-DNA interaction. It inhibits the growth of Hedgehog-dependent tumor cells, the self-renewal ability, and clonogenicity of tumor-derived stem cells.
