BEC CAS NO.63107-40-4

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BEC, also known as S-(2-boronoethyl)-L-cysteine, is a slow-binding competitive inhibitor of recombinant rat liver arginase I with Ki values of 0.4-0.6 μM from kinetic analyses. It significantly enhances NO-dependent relaxation of human penile corpus canvernosum smooth muscle in vitro at concentrations between 0.1-1.0 mM. BEC does not inhibit NO synthase, and effectively prevented ACh tolerance in aortic and mesenteric artery preparations.