United States
Premiumsupplier
Marein CAS NO.535-96-6
- Min.Order: 0
- Payment Terms:
- Product Details
Keywords
- Okanin-4'-O-glucoside
- 2-Propen-1-one, 3-(3,4-dihydroxyphenyl)-1-(4-(beta-D-glucopyranosyloxy)-2,3-dihydroxyphenyl)-, (E)-
Quick Details
- ProName: Marein
- CasNo: 535-96-6
- Molecular Formula: C21H22O11
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: 95%
- Storage: Store at 2-8°C, protect from light
- LimitNum: 0
Superiority
We provide customized and high-quality Marein product for your project.
Details
Marein is a glucoside chalcone with good antioxidant, anti-inflammatory, antihypertensive, antihyperlipidemic and antidiabetic effects. Marein has a neuroprotective effect because it reduces mitochondrial function damage and activates AMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. It scavenges DPPH radicals (IC50 = 48.35 μM) in a cell-free assay and is an EGFR and HDAC inhibitor with IC50s of 19.94 and 100 μM, respectively.
