Quick Details
- ProName: PPI-2458
- CasNo: 431077-35-9
- Molecular Formula: C22H36N2O6
- Application: For research use only.
- Purity: 95%
- LimitNum: 0
Superiority
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Details
PPI-2458 is a synthetic derivative of fumagillin with antineoplastic and cytotoxic properties. PPI-2458 irreversibly inhibits the enzyme methionine aminopeptidase type 2 (MetAP2), thereby preventing abnormal cell growth and angiogenesis. PPI-2458 is reported to have a better toxicity profile compared to other agents of its class.