- Product Details
Keywords
- 425386-60-3
- LY-450139
- stem cell
Quick Details
- ProName: Semagacestat
- CasNo: 425386-60-3
- Molecular Formula: C19H27N3O4
- Appearance: White to Off-white Solid
- Application: research use
- DeliveryTime: 7 days
- ProductionCapacity: 1 Kilogram/Month
- Purity: >98%
- Storage: Store in a cool and dry place and at 0...
- LimitNum: 1 Gram
Superiority
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
Details
Semagacestat is an inhibitor of the γ-secretase complex that blocks the production of Aβ38 (IC50 = 12.0 nM), Aβ40 (IC50 = 12.1 nM), and Aβ42 (IC50 = 10.9 nM) from H4 human glioma cells stably overexpressing human wild-type APP into the culture medium.