United States
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p-nitro-Pifithrin-α CAS NO.389850-21-9
- Min.Order: 1 Gram
- Payment Terms: L/C
- Product Details
Keywords
- 389850-21-9
- cas 389850-21-9
- p-nitro-PFT-α
Quick Details
- ProName: p-nitro-Pifithrin-α
- CasNo: 389850-21-9
- Molecular Formula: C15H15N3O3S·HBr
- Appearance: Crystalline Solid
- Application: research use
- DeliveryTime: 7 days
- ProductionCapacity: 1 Kilogram/Month
- Purity: ≥95%
- LimitNum: 1 Gram
Superiority
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
Details
p-nitro-Pifithrin-α is a cell-permeable p53 inhibitor. It blocks p53-mediated expression of p21/WAF1 and apoptosis in cortical neurons ten-fold more potently than pifithrin-α. It also suppresses p53-mediated TGF-β1 expression in human proximal tubular cells and attenuates steatosis and liver injury in mice fed a high-fat diet.