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EA4 CAS NO.389614-94-2
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Keywords
- 7-chloro-6-[4-(diethylamino)phenyl]-5,8-quinolinedione
Quick Details
- ProName: EA4
- CasNo: 389614-94-2
- Molecular Formula: C19H17ClN2O2
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥95%
- LimitNum: 0
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Details
EA4 is a rPLA2 inhibitor, and it is a quinone derivative. rPLA2, a calcium-dependent cytosolic phospholipase A2 (cPLA2), was initially isolated and characterized from bovine and human red blood cells (RBCs). EA4 inhibits the ionophore-induced arachidonic acid release from human and bovine red blood cells (RBCs), indicating that rPLA2 is responsible for the Ca2+-dependent release of arachidonic acid from mammalian RBCs.
