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3-Amino-1-propanesulfonic acid CAS NO.3687-18-1
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Keywords
- 3-aminopropane-1-sulfonic acid
Quick Details
- ProName: 3-Amino-1-propanesulfonic acid
- CasNo: 3687-18-1
- Molecular Formula: C3H9NO3S
- Appearance: Solid powder
- Application: Anti-Alzheimer agents; Amyloid-β inhib...
- Purity: 98%
- Storage: Store in a cool and dry place and at 0...
- LimitNum: 0
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Details
Tramiprosate, also nemed homotaurine, is an orally-administered, sulfated glycosaminoglycan mimic that targets amyloid β. γ-secretase: IC50 = 12 nM; Aβ40: IC50 = 7.4 nM; Aβ42: IC50 = 7.9 nM; gamma-secretase express: EC5050 = 7 nM (CHO cells); displacement of [3H]L685458 from human SPP express: IC50 = 28.7 μM (HEK293 cells).
