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D-NMAPPD CAS NO.35922-06-6
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Keywords
- (1R,2R)-B13
- CAY10466
Quick Details
- ProName: D-NMAPPD
- CasNo: 35922-06-6
- Molecular Formula: C23H38N2O5
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥98%
- LimitNum: 0
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Details
D-NMAPPD is an inhibitor of ceramidase. It induces cell death in SW403 colon adenocarcinoma cells in a time- and concentration-dependent manner but doesn't have effect on viability of rat hepatocytes, Kupffer cells, or sinusoidal endothelial cells when used at a concentration of 100 mM. It also increases intracellular ceramide accumulation and cytochrome C release and induces apoptosis in SW403 cells.
