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AY-NH2 CAS NO.352017-71-1
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Keywords
- PAR-4 Agonist Peptide, amide
- L-Alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide
Quick Details
- ProName: AY-NH2
- CasNo: 352017-71-1
- Molecular Formula: C34H48N8O7
- Application: For research use only.
- PackAge: 5 mg
- Purity: 98%
- Storage: Store at -20°C
- LimitNum: 0
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Details
AY-NH is a selective proteinase-activated receptor 4 (PAR4) receptor agonist peptide. It stimulates aggregation of rat and human platelets in vitro. It reduces expression of glycoprotein (GP) Ib, and increases expression of GPIIb/IIIa on the surface of human platelets. It induces relaxation of isolated rat aortic rings and contraction of rat gastric longitudinal muscle strips. It also inhibits calcium mobilization evoked by capsaicin in rat sensory neurons. It increases paw thickness in a rat paw edema inflammation model in vivo.
