United States
Premiumsupplier
Leukadherin-1 CAS NO.344897-95-6
- Min.Order: 0
- Payment Terms:
- Product Details
Keywords
- 4-[5-[[4-Oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]-2-furanyl]-benzoic acid
- Leukadherin-1
Quick Details
- ProName: Leukadherin-1
- CasNo: 344897-95-6
- Molecular Formula: C22H15NO4S2
- Appearance: Solid powder
- Application: For research use only.
- Purity: 95%
- Storage: Store in a cool and dry place (or refe...
- LimitNum: 0
Superiority
We provide customized and high-quality Leukadherin-1 product for your project.
Details
Leukadherin-1, also known as LA1, is a small molecule agonist that enhances CD11b/CD18-dependent cell adhesion to its ligand ICAM-1. Leukadherin-1 suppresses human innate inflammatory signalling. leukadherin-1 increases CD11b/CD18-dependent adhesion via membrane tethers. It also competitively inhibits YopH (Ki = 1.94 μM), a tyrosine phosphorylase secreted by Y. pestis into immune cells to block signal transduction, and anthrax lethal factor metalloproteinase, a component of anthrax toxin (IC50 = 6 μM).
