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Amitiza CAS NO.333963-40-9
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- Product Details
Keywords
- Prostan-1-oic acid, 11,15-epoxy-16,16-difluoro-15-hydroxy-9-oxo-, (11α,15R)-
- (11α,15R)-11,15-Epoxy-16,16-difluoro-15-hydroxy-9-oxoprostan-1-oic acid
Quick Details
- ProName: Amitiza
- CasNo: 333963-40-9
- Molecular Formula: C20H32F2O5
- Appearance: Off-white Solid
- Application: Chloride channel agonists
- PackAge: 100 mg
- Purity: ≥98%
- Storage: Store at -20°C
- LimitNum: 0
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Details
Lubiprostone, also known as RU-0211, is a new agent indicated for the treatment of patients with chronic constipation. It is a member of a new class of compounds called prostones. It was initially approved by the U.S. Food and Drug Administration (FDA) in 2006. Nonclinical studies demonstrated that lubiprostone exerts its effects on type-2 chloride channels (ClC-2), enhancing fluid secretion into the intestinal lumen.
