Quick Details
- ProName: JK-184
- CasNo: 315703-52-7
- Molecular Formula: C19H18N4OS
- Appearance: Light pink color
- Application: Differentiation
- PackAge: 100 mg
- Purity: 98%
- LimitNum: 0
Superiority
We provide customized and high-quality JK-184 product for your project.
Details
JK-184 is a potent downstream hedgehog (Hh) signaling antagonist that functions by alcohol dehydrogenase 7 (Adh7) inhibition, preventing Gli-dependent transcriptional activity (IC50 = 30 nM). Hedgehog signaling plays a key role in a wide variety of developmental processes as well as cancer progression. JK-184 exhibits antiproliferative activity.