United States
Premiumsupplier
Nocodazole CAS NO.31430-18-9
- Min.Order: 0
- Payment Terms:
- Product Details
Keywords
- methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate
- nocodazole
Quick Details
- ProName: Nocodazole
- CasNo: 31430-18-9
- Molecular Formula: C14H11N3O3S
- Appearance: Pale beige solid
- Application: For research use only.
- Purity: 95%
- Storage: Store in a cool and dry place and at 0...
- LimitNum: 0
Superiority
We provide customized and high-quality Nocodazole product for your project.
Details
Nocodazole, also called Oncodazole, reversibly inhibits microtubule polymerization so it has anti-neoplastic effect. It is inhibitor of Abl (IC50= 0.21 μM), Abl(E255K) (IC50= 0.53 μM)and Abl(T315I) (IC50= 0.53 μM).
in vitro: a high-affinity ligand for Abl phosphorylated (Kd= 0.091 μM), c-Kit (Kd= 1.6 μM), BRAF (Kd= 1.8 μM), and MEK (Kd= 1.6 μM)
in vivo: combined with Ketoconazole strongly enhances apoptosis of COLO 205 tumor xenografts
in vitro: a high-affinity ligand for Abl phosphorylated (Kd= 0.091 μM), c-Kit (Kd= 1.6 μM), BRAF (Kd= 1.8 μM), and MEK (Kd= 1.6 μM)
in vivo: combined with Ketoconazole strongly enhances apoptosis of COLO 205 tumor xenografts
