- Product Details
Keywords
- 302803-72-1
- HPI-4
- stem cell
Quick Details
- ProName: Ciliobrevin A
- CasNo: 302803-72-1
- Molecular Formula: C17H9Cl2N3O2
- Application: research use
- DeliveryTime: 7 days
- ProductionCapacity: 1 Kilogram/Month
- Purity: >98%
- LimitNum: 1 Gram
Superiority
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. #
Details
Ciliobrevin A is a Hedgehog (Hh) pathway inhibitor that blocks Hh pathway activation and decreases Smo ciliary accumulation in a constitutively active Hh cell line. It perturbs primary cilia formation, leads to disruption of Gli1/Gli2 activity, and suppresses primary cilia-related protein intraflagellar transport protein IFT88 expression. It inhibits cell proliferation, invasion and migration ability in human chondrosarcoma.