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Griffipavixanthone CAS NO.219649-95-3
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- Product Details
Keywords
- Indeno[1,2-a]xanthen-13(8H)-one,8a,9,10,12a-tetrahydro-1,3,6,7-tetrahydrox
y-9,9,11-trimethyl-8-(3,4,6,8-tetrahydroxy-9-oxo-9H-xanthen-1-yl)-,(8R,8aR,12aS)-rel-(+)-
Quick Details
- ProName: Griffipavixanthone
- CasNo: 219649-95-3
- Molecular Formula: C36H28O12
- Appearance: Brown powder
- Application: anti-non-small cancer
- PackAge: 1 mg
- Purity: >98%
- LimitNum: 0
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Details
Griffipavixanthone is a natural xanthone found in the fruits of Garcinia oblongifolia Champ, it inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, with IC50 values of 3.03 ± 0.21 μM at 48h, it induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS production; which demonstrates that the potential application of griffipavixanthone as an anti-non-small cell lung cancer agent.
