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YKL-06-061 CAS NO.2172617-15-9
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Keywords
- YKL06-061
- YKL 06-061
Quick Details
- ProName: YKL-06-061
- CasNo: 2172617-15-9
- Molecular Formula: C30H37N7O2
- Application: a potential dermatologic drug
- PackAge: 50 mg
- Purity: 95%
- LimitNum: 0
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Details
YKL-06-061 is a small molecule serine/threonine-protein kinase SIK1 inhibitor (Ki = 6.56 nM) that is hopefully developed to be a dermatologic drug impacting UV protection and skin cancer risk. It causes a dose-dependent increase in microphthalmia-associated transcription factor (MITF) mRNA expression during 3-hour function in normal human melanocytes, UACC62 human melanoma cells, and UACC257 human melanoma cells.
