Keywords
- S-303 dihydrochloride
- 2-[Bis(2-chloroethyl)amino]ethyl N-9-acridinyl-β-alaninate dihydrochloride
Quick Details
- ProName: Amustaline dihydrochloride
- CasNo: 210584-54-6
- Molecular Formula: C22H27Cl4N3O2
- Appearance: Solid
- Application: For research use only.
- Purity: ≥97%
- Storage: Store at 2-8°C for short term (days to...
- LimitNum: 0
Superiority
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Details
Amustaline dihydrochloride is a nucleic acid targeted alkylator that is an effective pathogen inactivation agent for blood components containing red blood cells. It has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products).