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OBI-3424 CAS NO.2097713-68-1
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Keywords
- TH-3424
- Phosphinic acid, P,P-bis(1-aziridinyl)-, (1R)-1-(3-(3-((dimethylamino)carbonyl)phenoxy)-4-nitrophenyl)ethyl ester
Quick Details
- ProName: OBI-3424
- CasNo: 2097713-68-1
- Molecular Formula: C21H25N4O6P
- Appearance: Solid Powder
- Application: For research use only.
- Purity: ≥95%
- Storage: Store at -20°C, protect from light
- LimitNum: 0
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Details
OBI-3424 is a highly selective prodrug that is converted by AKR1C3 (aldo-keto reductase 1C3) to a potent DNA-alkylating agent. It can be used in studies of hepatocellular carcinoma, castrate-resistant prostate cancer, and acute lymphoblastic leukemia (ALL).
