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Darunavir CAS NO.206361-99-1
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- Product Details
Keywords
- cas 206361-99-1
- 206361-99-1
- TMC-114
Quick Details
- ProName: Darunavir
- CasNo: 206361-99-1
- Molecular Formula: C27H37N3O7S
- Appearance: White to Pale Beige Solid
- Application: Inhibitor
- ProductionCapacity: Metric Ton/Day
- Purity: 98%
- LimitNum: 0 Metric Ton
Superiority
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GMP factory Packing with pallet as buyer's special request Best service after shipment with e-mail Cargos together with container sales seervice available Api, inhibitor, and fine chemicals for more than 6 years. |
Details
Darunavir is a second generation protease inhibitor that targets the HIV-1 protease. It demonstrates extremely potent activity against the infectivity and replication of various strains of HIV-1, including several that are resistant to first generation protease inhibitors (IC50s = 3-30 nM). Darunavir has been reported to inhibit both cell-free diffusion and cell-to-cell spread of HIV-1 with IC50 values of 2.5 and 2.8 nM, respectively.