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GDC-0077 CAS NO.2060571-02-8
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Keywords
- GDC 0077
- GDC0077
Quick Details
- ProName: GDC-0077
- CasNo: 2060571-02-8
- Molecular Formula: C18H19F2N5O4
- Application: For research use only.
- PackAge: 100 mg
- Purity: 95%
- Storage: Store in a cool and dry place (or refe...
- LimitNum: 0
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Details
GDC-0077 is an orally available and selective PI3K inhibitor (IC50 = 0.038 + 0.003 nM) with > 300-fold selective over other Class I PI3K isoforms. GDC-0077 exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3.
