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T 98475 hydrochloride CAS NO.192887-28-8
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Keywords
- Thieno[2,3-b]pyridine-5-carboxylic acid, 7-[(2,6-difluorophenyl)methyl]-4,7-dihydro-2-[4-[(2-methyl-1-oxopropyl)amino]phenyl]-3-[[methyl(phenylmethyl)amino]methyl]-4-oxo-, 1-methylethyl ester, hyd...
- Thieno[2,3-b]pyridine-5-carboxylic acid, 7-[(2,6-difluorophenyl)methyl]-4,7-dihydro-2-[4-[(2-methyl-1-oxopropyl)amino]phenyl]-3-[[methyl(phenylmethyl)amino]methyl]-4-oxo-, 1-methylethyl ester, mon...
Quick Details
- ProName: T 98475 hydrochloride
- CasNo: 192887-28-8
- Molecular Formula: C37H37F2N3O4S.HCl
- Application: For research use only.
- Purity: ≥95%
- Storage: Store at 2-8°C
- LimitNum: 0
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Details
T 98475 is a potent, orally active and non-peptide gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist (IC50 = 0.2, 4.0 and 60 nM for human, monkey and rat GnRH receptors, respectively). T 98475 inhibits LH release in vitro (IC50 = 100 nM) and reduces plasma LH concentration in castrated male cynomolgus monkeys.
