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TAPI-2 CAS NO.187034-31-7
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Keywords
- TNF Protease Inhibitor 2
- N-[(2S)-1-[[(2S)-1-(2-Aminoethylamino)-1-oxopropan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)butanediamide
Quick Details
- ProName: TAPI-2
- CasNo: 187034-31-7
- Molecular Formula: C19H37N5O5
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥95%
- Storage: 4°C, sealed storage, away from moistur...
- LimitNum: 0
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Details
TAPI-2 is a broad-spectrum inhibitor of TNF-α converting enzyme (TACE; ADAM17), other ADAMs and matrix metalloproteinases (MMPs). It inhibits phorbol-12-myristate-13-acetate-induced (PMA) shedding of various cell surface proteins, such as TGF-α, β amyloid precursor protein, L-selectin, and IL-6 receptor α subunit.
