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Conoidin A CAS NO.18080-67-6
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Keywords
- 2,3-Bis(bromomethyl)quinoxaline 1,4-dioxide
Quick Details
- ProName: Conoidin A
- CasNo: 18080-67-6
- Molecular Formula: C10H8Br2N2O2
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥98%
- LimitNum: 0
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Details
Peroxiredoxins are a ubiquitous family of antioxidant enzymes that also control cytokine-induced peroxide levels and thereby mediate signal transduction in mammalian cells. Conoidin A inactivates peroxiredoxins by covalently binding to the catalytic cysteine on the enzyme. It has been shown to inhibit peroxiredoxin II (IC50 = 23 μM) in the parasite T. gondii and peroxiredoxin I in the hookworm A. ceylanicum.
