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SLC-0111 CAS NO.178606-66-1
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Keywords
- 4-(3-(4-fluorophenyl)ureido)benzenesulfonamide
- SLC-0111
Quick Details
- ProName: SLC-0111
- CasNo: 178606-66-1
- Molecular Formula: C13H12FN3O3S
- Appearance: Solid powder
- Application: For research use only.
- PackAge: 50 mg
- Purity: 95%
- Storage: Store in a cool and dry place (or refe...
- LimitNum: 0
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Details
SLC-0111, also known as U-104, MST-104 and NSC 213841, is a potent carbonic anhydrase (CA) inhibitor (Ki values are 4.5, 45.1, 5080 and 9640 nM for CA XII, CA IX, CA I and CA II respectively in MDA-MB-231 cells). U-104 associates with CAIX/CAXII only under hypoxic conditions in vivo, reducing extracellular acidity and resulting in significant inhibition of tumor growth and metastasis in experimental models.
