ELA-32 (human) CAS NO.1680205-79-1

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ELA-32 (human) is a potent apelin receptor agonist (IC50 = 0.27 nM; Kd = 0.51 nM) stimulating the PI3K/AKT pathway and promoting self-renewal of hESCs via cell-cycle progression and protein translation. It also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage.