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SEL120-34A monohydrochloride CAS NO.1609452-30-3
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Keywords
- 7,8-Dibromo-9-methyl-2-piperazin-1-yl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline Hydrochloride
- 4H-Imidazo(4,5,1-ij)quinoline, 7,8-dibromo-5,6-dihydro-9-methyl-2-(1-piperazinyl)-, hydrochloride (1:1)
Quick Details
- ProName: SEL120-34A monohydrochloride
- CasNo: 1609452-30-3
- Molecular Formula: C15H19Br2ClN4
- Application: For research use only.
- Purity: ≥98%
- Storage: Store at 2-8°C, sealed storage, away f...
- LimitNum: 0
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Details
SEL120-34A monohydrochloride is an ATP-competitive and orally bioavailable inhibitor of Cyclin-dependent kinase 8 (CDK8), showing selectivity for CDK8/Cyclin C and CDK19/Cyclin C with IC50s of 4.4 nM and 10.4 nM, respectively. It has anti-tumor activity.
