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BMS-986165 CAS NO.1609392-27-9
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Keywords
- Tyk2-IN-4
- BMS 986165
Quick Details
- ProName: BMS-986165
- CasNo: 1609392-27-9
- Molecular Formula: C20H19D3N8O3
- Application: For research use only.
- PackAge: 100 mg
- Purity: 98%
- LimitNum: 0
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Details
BMS-986165 is a potent and selective TYK2 inhibitor that blocks signal transduction of IL-23, IL-12, and type I IFNs. It binds to the Tyk2 pseudokinase domain (Ki = 0.02 nM), and is highly selective against a panel of 265 kinases and pseudokinases. BMS-986165 is under a phase III clinical trial for the treatment of Psoriasis.
