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THZ2 CAS NO.1604810-84-5
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Keywords
- N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]benzamideTHZ2
- THZ 2
Quick Details
- ProName: THZ2
- CasNo: 1604810-84-5
- Molecular Formula: C31H28ClN7O2
- Appearance: Solid powder
- Application: For research use only.
- Purity: 95%
- Storage: Store in a cool and dry place and at 0...
- LimitNum: 0
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Details
THZ2, an analog of THZ1, with the potential to treat Triple-negative breast cancer (TNBC), it is a potent and selective CDK7 inhibitor which overcomes the instability of THZ1 in vivo.
IC50: CDK7= 13.9 nM; TNBC cells= 10 nM
IC50: CDK7= 13.9 nM; TNBC cells= 10 nM
