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TX1-85-1 CAS NO.1603845-32-4
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- Product Details
Keywords
- EX-A2880
- N-[5-[1-[4-(4-Acetylpiperazin-1-yl)cyclohexyl]-4-aminopyrazolo[3,4-d]pyrimidin-3-yl]-2-phenoxyphenyl]prop-2-enamide
Quick Details
- ProName: TX1-85-1
- CasNo: 1603845-32-4
- Molecular Formula: C32H36N8O3
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥98%
- LimitNum: 0
Superiority
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Details
TX1-85-1 is an inhibitor of the epidermal growth factor receptor tyrosine kinase ErbB3 (IC50 = 23 nM). It is the first selective HER3 ligand that interacts with cys721 in the ATP-binding pocket of HER3.
