United States
Premiumsupplier
ISRIB CAS NO.1597403-47-8
- Min.Order: 0
- Payment Terms:
- Product Details
Keywords
- 2-(4-chlorophenoxy)-N-[4-[[2-(4-chlorophenoxy)acetyl]amino]cyclohexyl]acetamide
2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide
ISRIB compound
trans-ISRIB
Quick Details
- ProName: ISRIB
- CasNo: 1597403-47-8
- Molecular Formula: C22H24Cl2N2O4
- Appearance: White solid
- Application: For research use only.
- PackAge: 250 mg
- Purity: 95%
- Storage: Store in a cool and dry place and at 0...
- LimitNum: 0
Superiority
We provide customized and high-quality ISRIB product for your project.
Details
ISRIB is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated.
