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Ipatasertib HCl CAS NO.1489263-16-2
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- Product Details
Keywords
- (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one hydrochloride.
- GDC0068
Quick Details
- ProName: Ipatasertib HCl
- CasNo: 1489263-16-2
- Molecular Formula: C24H33Cl2N5O2
- Appearance: Solid powder
- Application: For research use only.
- Purity: 95%
- Storage: Store in a cool and dry place (or refe...
- LimitNum: 0
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Details
Ipatasertib, also known as GDC-0068, is a highly selective pan-Akt inhibitor targeting Akt1/2/3 (IC50= 5 nM/18 nM/8 nM in cell-free assays) with 620-fold selectivity over PKA. Ipatasertib is advancing in clinical development including a Phase 3 trial in patients with prostate cancer and three Phase 2 trials in patients with breast cancer, gastric cancer and prostate cancer.
