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bpV(pic) potassium hydrate CAS NO.148556-27-8
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Keywords
- Bisperoxovanadium(pic)
Quick Details
- ProName: bpV(pic) potassium hydrate
- CasNo: 148556-27-8
- Molecular Formula: C6H4NO7V·2K·2H2O
- Appearance: Crystalline Solid
- Application: For research use only.
- Purity: ≥96%
- LimitNum: 0
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Details
BpV(pic) is composed of a vanadate molecule coordinated to picolinic acid (2-carboxypyridine) and potassium. It is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs) with IC50 of 31 nM. It is also known to be an insulin mimetic capable of activating the insulin receptor kinase of cultured hepatoma cells and stimulating lipogenesis in adipocytes. BpV(pic) has been shown to activate the insulin receptor kinase (IRK) of cultured hepatoma cells and is also an inhibitor of G6Pase.
