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IRE1α kinase-IN-2 CAS NO.1414938-21-8
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Keywords
- 1-(4-(8-Amino-3-isopropylimidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl)-3-(3-(trifluoromethyl)phenyl)urea
- Urea, N-[4-[8-amino-3-(1-methylethyl)imidazo[1,5-a]pyrazin-1-yl]-1-naphthalenyl]-N'-[3-(trifluoromethyl)phenyl]-
Quick Details
- ProName: IRE1α kinase-IN-2
- CasNo: 1414938-21-8
- Molecular Formula: C27H23F3N6O
- Application: For research use only.
- Purity: ≥95%
- LimitNum: 0
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Details
IRE1α kinase-IN-2, a potent IRE1α kinase inhibitor (EC50 = 0.82 μM), inhibits IRE1α kinase autophosphorylation (IC50 = 3.12 μM), and inhibits XBP1 mRNA splice in WT cell lines.
