Angiotensin III (human, mouse) CAS NO.13602-53-4

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Angiotensin III (Ang III) is generated from Ang II by APA (and subsequently degraded by aminopeptidase N), and that central Ang III seems to play a key-role in vasopressin release and BP control. Angiotensin III, human, mouse is a heptapeptide agonist, which acts as an endogenous angiotensin type 2 receptor (AT2R) agonist. The IC50 values for AT2R is 0.648 nM and the IC50 values for AT1R is 21.1 nM. The biologically active COOH-terminal heptapeptide angiotensin III is bound more tightly than angiotensin II.