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UNC9994 CAS NO.1354030-51-5
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Keywords
- 5-(3-(4-(2,3-dichlorophenyl)piperidin-1-yl)propoxy)benzo[d]thiazole
- Benzothiazole, 5-[3-[4-(2,3-dichlorophenyl)-1-piperidinyl]propoxy]-
Quick Details
- ProName: UNC9994
- CasNo: 1354030-51-5
- Molecular Formula: C21H22Cl2N2OS
- Appearance: Solid Powder
- Application: For research use only.
- Purity: ≥98%
- Storage: Store at 2-8°C for short term (days to...
- LimitNum: 0
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Details
UNC9994, an analog of Aripiprazole, is a functionally selective β-arrestin-biased dopamine D2 receptor (D2R) agonist with EC50s <10 nM for β-arrestin-2 recruitment to D2 receptors. UNC9994 is both β-arrestin-2 translocation partial agonist and Gi-regulated cAMP production antagonist, and has strong antipsychotic drug-like activity in vivo.
